Cytokine profile in elderly patients with sepsis
نویسندگان
چکیده
منابع مشابه
Th1, Th2 and Th17 Cytokine Profile in Patients with Multiple Sclerosis Following Treatment with Rapamycin
Background: Management of multiple sclerosis (MS) is based on the usage of immunosuppressive and immune-modulating medications. Cytokines play an important role in the pathogenesis of MS. Objective: To evaluate the effects of rapamycin on the concentrations of Th1/Th2/Th17 serum cytokines in patients with MS. Methods: Six patients with relapsing remitting MS as a case group and 6 healthy indivi...
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In 35 patients fulfilling the criteria of systemic inflammatory response syndrome (SIRS) of infectious origin, tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), tumor necrosis factor-soluble receptor (TNF-sR), and interleukin-12 (IL-12), C-reactive protein (CRP) levels and the Acute Physiology, and Chronic Health Evaluation III score (APACHE III) were determined on days 1 to 7, 14,...
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INTRODUCTION Severe sepsis in humans may be related to an underlying profound immune suppressive state. We investigated the link between gene expression of immune regulatory cytokines and the range of illness severity in patients with infection and severe sepsis. METHODS A prospective observational study included 54 ICU patients with severe sepsis, 53 patients with infection without organ fai...
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BACKGROUND Advanced age is one of the factors that increase mortality in intensive care. Sepsis and multi-organ failure are likely to further increase mortality in elderly patients.We compared the characteristics and outcomes of septic elderly patients (> 65 years) with younger patients (≤ 65 years) and identified factors during the first 24 hours of presentation that could predict mortality in...
متن کاملProlonged overexpansion of extracellular water in elderly patients with sepsis.
OBJECTIVE To compare the sequential changes in extracellular water (ECW) expansion in elderly patients receiving intensive care for severe sepsis with those in a similar group of younger patients. DESIGN Inception cohort study. SETTING Critical Care Unit and University Department of Surgery in a single tertiary care center. PATIENTS A consecutive series of 14 patients older than 60 years ...
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ژورنال
عنوان ژورنال: Indian Journal of Critical Care Medicine
سال: 2009
ISSN: 0972-5229,1998-359X
DOI: 10.4103/0972-5229.56052